New Data on Human Macrophages Polarization by Hymenolepis diminuta Tapeworm—An In Vitro Study

New Data on Human Macrophages Polarization by Hymenolepis diminuta Tapeworm—An In Vitro Study

Helminths and their products can suppress the host immune response to escape host defense mechanisms and establish chronic infections. Current studies indicate that macrophages play a key role in the immune response to pathogen invasion. They can be polarized into two distinct phenotypes: M1 and M2. The present paper examines the impact of the adult Hymenolepis diminuta (HD) tapeworm and its ex...

Studies on Malic Enzyme from Hymenolepis Diminuta

Influence of trifluoperazine on tegument membranes in Hymenolepis diminuta.

Using immuno electron microscopy we have identified a number of calmodulin/calmodulin binding proteins distributed at various subcellular sites (Eastlake et al, 1994). Treatment of H. diminuta with trifluoperazine has potential cestocidal properties influencing both tegumental protein release, activity of calmodulindependent enzymes and the uptake of glucose (Branford White & Hipkiss, 1985; Hip...

Human infection with Hymenolepis diminuta: case report from Spain.

We report a case of Hymenolepis diminuta infection in a human. The patient was a 5-year-old girl referred to us through the onset of a cyanotic attack. Treatment with a single dose (10 mg/kg of body weight) of praziquantel was ineffective, but the parasite was eradicated after three treatment cycles with the same drug at dosages of 25 mg/kg/day for 5 days.

In Vitro Anthelmintic Effects of Senna Occidentalis (l.) Link (leguminosae) on Rat Tapeworm Hymenolepis Diminuta

Objective: This study was conducted to evaluate the anthelmintic activity of ethanolic leaf extract of Senna occidentalis on rat tapeworm Hymenolepis diminuta. Methods: Adult H. diminuta worms were obtained from laboratory maintained infection in rats. Different concentrations of crude ethanolic leaf extracts of S. occidentalis were tested in vitro on H. diminuta and praziquantel (PZQ) was used...